300 hypothyroidism symptoms: count how many you have

300 hypothyroidism symptoms: count how many you have

The World Health Organization estimates that there are 750 million people with thyroid dysfunction worldwide, and The American Thyroid Association writes up to 60 percent of those with thyroid disease are UNAWARE of their condition. While the statistics show that women are more likely to develop thyroid disease, thyroid disease is a condition that affects women, men, and children of all ages.

Of the 750 million people with thyroid dysfunction, 1.2 million of them are currently following my site Hypothyroid Mom (I won’t stop until I find all 750 million). The majority are here because they are still feeling unwell despite standard hypothyroidism treatment. Most are told their thyroid is “fine” while they struggle with a countless number of symptoms. Often times their doctors have no clue the vast array of symptoms that can befall a thyroid patient and most patients have no idea their symptoms could possibly be a red flag that their condition is not being well treated. Some may back down from speaking up to their doctor because they feel “doctor knows best” or that they don’t have any scientific proof to back up their claims…until now.

The first step before anything with hypothyroidism is to know the symptoms. There are over 300. Yes you read that correctly. Every single cell of the body requires thyroid hormone for proper functioning, so every single part of the body is vulnerable when you have abnormal thyroid function.

Knowing the symptoms is more powerful than you can imagine.

Of course not every single symptom you experience is caused by your thyroid. And not everyone will present with the exact same symptoms. It’s an interesting thing really how thyroid disease can present in different ways in different people. However, if you experience a high number of these symptoms overall and you haven’t been given a solid medical reason to explain them all, then you know you may be on to something. It may be your thyroid.

At my lowest point with hypothyroidism when I could barely keep my eyes open through the day, I suffered from 118 symptoms on this list. I was a walking billboard for hypothyroidism, yet my doctor at that time insisted my thyroid was “normal”. Now thanks to optimal thyroid treatment including all the many pieces of the thyroid puzzle that I include at Hypothyroid Mom, which also meant researching the best thyroid doctors on the planet (and I’m blessed to include so many of them as guest writers on my website), the majority of my symptoms have completely disappeared. I just recently counted the number of symptoms that I experience and I only have 15 left that persist but even then most of the 15 are greatly improved. I am over the moon happy about feeling well with hypothyroidism and so thankful.

Now come on, let’s get you well too.

If you are experiencing a high number of the symptoms on this list, then this is your big red flag (and I’m waving it wildly at you) that, one, you have hypothyroidism that hasn’t been diagnosed or, two, you have diagnosed hypothyroidism but it is miserably treated.

More than likely for the first time in the history of your disease, you will see a full list of possible symptoms in front of you and you will probably have close to 100 in total or more symptoms that you had no idea could be related to your thyroid.

When your doctor insists, “Your thyroid is fine.”

Now, you can shoot back, “No it’s not.” And you have proof.

I have spent more days than you can imagine creating this article, carefully putting together a list of scientific studies to back up the symptoms on this list so that you have them at the ready to show your doctor as your proof. There is no way a doctor can swiftly dismiss your concerns when you walk in armed with the comprehensive list of the most recent scientific studies that I’ve listed at the bottom of this article.

Even if your current doctor refuses to help despite this, you will know without a shadow of a doubt that you need to find an open-minded thyroid doctor. Even if that means firing ten doctors until you find the one that helps.

I hope this article above all others at Hypothyroid Mom, passes the power of healing into your hands. Your symptoms are not all in your head. No, you are not crazy or lazy or faking, even if other people make you feel that way. Convincing yourself of this can change your world.

I’ve included at the bottom of each section an area to score yourself. I want you to count how many of the symptoms that I’ve listed for each section that you actually struggle with yourself. At the end, you will be adding up your total score out of 310.

I know this is a seriously long list, but getting that final score may very well shock you and (my great hope) spur you into the biggest wellness journey of your life. Remember to count your symptoms again over time to track your improvements as you learn more about effective thyroid treatment at Hypothyroid Mom.

You may be wondering how to print this article or any other article at Hypothyroid Mom. Go to the article you wish to print, then select File then Print or type command P. This will open a printing window where you select your settings and print.

Symptoms of Hypothyroidism: Energy & Sleep

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Weight

symptoms of hypothyroidism

YOUR SCORE: ______

Symptoms of Hypothyroidism: Body Temperature

Symptoms of hypothyroidism

YOUR SCORE: ______

Symptoms of Hypothyroidism: Vulnerability to Infections

Symptoms of hypothyroidism

YOUR SCORE: ______

Symptoms of Hypothyroidism: Multiple Autoimmune Diseases

Symptoms of hypothyroidism

YOUR SCORE: ______

Symptoms of Hypothyroidism: Teeth, Mouth, Throat

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Ears

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Eyes

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Hair

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Legs, Arms, Feet, Hands

Symptoms of hypothyroidism


YOUR SCORE: ______

Symptoms of Hypothyroidism: Skin

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Digestion

Symptoms of hypothyroidism

YOUR SCORE: ______

Symptoms of Hypothyroidism: Pain

Symptoms of hypothyroidism

YOUR SCORE: ______

Symptoms of Hypothyroidism: Menstrual Problems

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Fertility, Pregnancy & Postpartum

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Brain

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Kidney & Bladder

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Symptoms of Hypothyroidism: Liver & Gallbladder

Symptoms of hypothyroidism

YOUR SCORE: ______

Symptoms of Hypothyroidism: Lungs

300 hypothyroidism symptoms: count how many you have


YOUR SCORE: ______

Symptoms of Hypothyroidism: Heart

300 hypothyroidism symptoms: count how many you have

YOUR SCORE: ______

Now add up all your individual scores to get your total number of hypothyroidism symptoms out of the 310 listed.

Your Total Hypothyroidism Symptoms Score:

______ / 310

Are you shocked?

I knew you would be.

Hypothyroidism Symptoms in Recent Scientific Literature:

Energy & Sleep

Basoglu, O.K., Tasbakan, M.S. Gender difference in clinical and polysomnographic features of obstructive sleep apnea: a clinical study of 2827 patients. Sleep Breath. 2017 Feb 14.

Chaker, L., et al. Hypothyroidism. Lancet. 2017 Sep 23;390(10101):1550-1562.

Cohen, A., et al. Comorbidities in a community sample of narcolepsy. Sleep Med. 2018 Mar;43:14-18.

Dunn, D., Turner, C. Hypothyroidism in Women. Nurs Womens Health. 2016 Feb-Mar;20(1):93-8.

Misiolek, M., et al. Sleep apnea syndrome and snoring in patients with hypothyroidism with relation to overweight. J Physiol Pharmacol. 2007 Mar;58 Supplements 1:77-85.

Petrone, A., et al. Abnormal thyroid hormones and non-thyroidal illness syndrome in obstructive sleep apnea, and effects of CPAP treatment. Sleep Med. 2016 Jul;23:21-25.

Sethi, B., et al. The Thyroid Registry: Clinical and Hormonal Characteristics of Adult Indian Patients with Hypothyroidism. Indian J Endocrine Metab. 2017 Mar-Apr;21(2):302-307.

Louwerens, M. et al. Fatigue and fatigue-related symptoms in patients treated for different causes of hypothyroidism. Eur J Endocrinol. 2012 Dec;167(6):809-15.


Harbuwono, D.S., et al. Improvement of Metabolic Parameters Resulted from Levothyroxine Therapy in Hypothyroid Type 2 Diabetes Mellitus Patient. Acta Med Indones. 2016 Apr;48(2):145-7.

Laurberg, P., et al. Thyroid Function and Obesity. Eur Thyroid J. 2012 Oct;1(3):159-167.

Mullur, R., et al. Thyroid Hormone Regulation of Metabolism. Physiol Rev. 2014 Apr;94(2):355-382.

Ozair, M., et al. Prevalence of thyroid disorders in North Indian Type 2 diabetic subjects: A cross sectional study. Diabetes Metab Syndr. 2017 Dec 20. pii: S1871-4021(17)30421-6.

Răcătăianu, N., et al. Thyroid disorders in obese patients. Does insulin resistance make a difference? Arch Endocrinol Metab. 2017 Dec;61(6):575-583.

Subekti, I., et al. Thyroid Dysfuntion in Type 2 Diabetes Mellitus Patients. Acta Med Indones. 2017 Oct-49(4):314-323.

Witkowska-Sędek, E., et al. Thyroid dysfunction in obese and overweight children. Endokrynol Pol. 2017;68(1):54-60.

Body Temperature

Obermeyer, Z., et al. Individual differences in normal body temperature: a longitudinal big data analysis of patient records. BMJ. 2017 Dec 13;359:j5468.

Warner, A., et al. Inappropriate heat dissipation ignites brown fat thermogenesis in mice with a mutant thyroid hormone receptor α1. Proc Natl Acad Sci USA. 2013 Oct 1;110(40):16241-6.

Warner, A., Mittag, J. Brown fat and vascular heat dissipation. Adipocyte. 2014 Jul 1; 3(3): 221–223.

Vulnerability to Infections

Günel, C., et al. [The relationship between hypothyroidism and rhinitis]. Kulak Burun Bogaz Ihtis Derg. 2010 Jul-Aug;20(4):163-8.

Khan, Q., et al. Prevalence of Hepatitis B and C infection in autoimmune thyroid patients. Journal of Entomology and Zoology Studies. 2017;5(2):1335-1337.

Nóbrega, M.M., et al. Bacteriuria and urinary tract infection after female urodynamic studies: risk factors and microbiological analysis. Am J Infect Control. 2015 Oc 1;43(10):1035-9.

Ren, H., et al. The non-thyroidal illness syndrome is associated with postoperative surgical site infections in enterocutaneous fistulae. Int J Surg. 2018 Feb 7;51:213-217.

Multiple Autoimmune Diseases

Anoop, J., et al. Unravelling thyroid dysfunction in rheumatoid arthritis: History matters. Int J Rheum Dis. 2018 March;21(3):688-692.

Barmpari, M.E., et al. Thyroid Dysfunction among Greek Patients with Type 1 and Type 2 Diabetes Mellitus as a Disregarded Comorbidity. J Diabetes Res. 2017;2017:6505814.

Edwards, N.C., et al. Comorbidity in US patients with multiple sclerosis. Patient Relat Outcome Meas. 2018 Feb 13;9:97-102.

Norström, F., at al. The Impact of Thyroid Autoimmunity on Thyroid function in 12-year-old Children with Celiac Disease. J Pediatr Gastroenterol Nutr. 2018 Jan 25.

Solanki, K.K., et al. High Prevalence of Antithyroid Antibodies in a New Zealand Cohort of Patients with Systemic Sclerosis. J Clin Rheumatol. 2018 Feb 15.

Vachiramon, V., et al. Prevalence of Thyroid Abnormalities in Thai Patients with Vitiligo. Biomed Res Int. 2017;2017:7502935.

Teeth, Mouth, Throat

Costa, C., et al. A systemic disease un…suspected by physical examination. BMJ Case Report. 2014 Oct 9;2014.

Dudhia, S.B., Dudhia, B.B. Undetected hypothyroidism: A rare dental diagnosis. J Oral Maxillofac Pathol. 2014 May;18(2):315-9.

Hamdan, A.L., et al. Phonatory symptoms and impact on quality of life in female patients with goiter. Ear Nose Throat J. 2016 Jul;95(7):E5-E10.

Li, D., et al. The Association of Thyroid Disease and Oral Lichen Planus: A Literature Review and Meta-analysis. Front Endocrine (Lausanne). 2017 Nov 9;8:310.

Naik, M.M., Vassandacoumara, V. Qualitative and quantitative salivary changes and subjective oral dryness among patients with thyroid dysfunction. Indian J Dent Res. 2018 Jan-Feb;29(1):16-21.

Simmons, L.H., et al. Case 38-2014: A man with sore throat, hoarseness, fatigue, and dyspnea. N Engl J Med. 2015 Mar 5;372(10):982.

Tong, H.J., et al. Management of a child with severe hypodontia in th mixed dentition stage of development. Our Arch Paediatr Dent. 2014 Dec;15(6):449-54.

Venkatesh Babu, N.S., Patel, P.B. Oral health status of children suffering from thyroid disorders. J Indian Soc Pedod Prev Dent. 2016 Apr-Jun;34(2):139-44.

Wémeau, J.L., et al. [Oral and dental expression of thyroid diseases]. Presse Med. 2017 Sep;46(9):864-868.


Andrade, C.L.O., et al. Mechanisms involved in hearing disorders of thyroid ontogeny: a literature review. Arch Endocrine Metab. 2017 Setp-Oct;61(5):501-505.

Kim, H.J., et al. Analysis of the prevalence and associated risk factors of tinnitus in adults. PLoS One. 2015 May 28;10(5):e0127578.

Messina, A., et al. Italian survey on benign paroxysmal positional vertigo. Acta Otorhinolaryngol Ital. 2017 Aug;37(4):328-335.

Orhan, I., et al. Tympanometric changes and eustachian tube function in patients with hypothyroidism. J Craniofac Surg. 2014 May;25(3):e230-3.

Santosh, U.P., Rao, M.S. Incidence of Hypothyroidism in Meniere’s Disease. J Clin Diagn Res. 2016 May;10(5):MC01-3.

Wojtczak, R., et al. Epidemiology of dizziness in northern Poland – The first Polish neurootologic survey of the general population. Ann Agric Environ Med. 2017 Sep 21;24(3):502-506.


Choi, H.Y., et al. Recurrent oculomotor neuritis related to autoimmune hypothyroidism. Case Report. Neuro Endocrinol Lett. 2015;36(4):303-5.

Ju, C., Zhang, L. Diplopia in a patient with Hashimoto’s thyroiditis: A case report and literature review. Medicine (Baltimore). 2017 Jun;96(26):e7330.

Wang, S., et al. Hypothyroidism as a risk factor for open angle glaucoma: A systematic review and meta-analysis. PLoS One. 2017 Oct 25;12(10):e0186634.


Bin Saif, G.A. Severe subtype of alopecia areata is highly associated with thyroid autoimmunity. Saudi Med J. 2016 Jun;37(6):656-61.

Contreras-Jurado, C., et al. Impaired Hair Growth and Wound Healing in Mice Lacking Thyroid Hormone Receptors. PLoS One. 2014;9(9):e108137.

Contreras-Jurado, C., et al. Thyroid hormone signaling controls hair follicle stem cell function. Mol Biol Cell. 2015 Apr 1;26(7):1263-72.

Siah, T.W., et al. Female Pattern Hair Loss: A Retrospective Study in a Tertiary Referral Center. Int J Trichology. 2016 Apr-Jun;8(2):57-61.

Wolff, H., et al. The Diagnosis and Treatment of Hair and Scalp Diseases. Dtsch Arztebl Int. 2016 May 27;113(21):377-86.

Legs, Arms, Feet, Hands

Aishwarya, K., et al. Clinical Signs in Hypothyroidism – Myoedema and Woltman Sign. QJM. 2017 Nov 28.

Bano, A., et al. Gait patterns associated with thyroid function: The Rotterdam Study. Sci Rep. 2016 Dec 14:6:38912

Razi, A., et al. Evaulation of dermal symptoms in hypothyroidism and hyperthyroidism. Pak J Biol Sci. 2013 Jun 1;16(11):541-4.


Al-Arashi, W., et al. [A man who was unable to open his eyes]. Ned Tijdschr Geneeskd. 2018;162(0):D2176.

Firouzi, A., et al. The Combined Effects of Levothyroxine and Low Level Laser Therapy on Wound Healing in Hypothyroidism Male Rat Model. J Lasers Med Sci. 2018 Winter;9(1):7-10.

Haritha, S., Kirthi Sampath, K. Skin Manifestations of Hypothyroidism-A Clinical Study. Journal of Dental and Medical Sciences. 2013 May-Jun;7(2):58-60.

Lause, M., et al. Dermatologic manifestations of endocrine disorders. Transl Pediatr. 2017 Oct;6(4):300-312.

Keen, M.A., et al. A Clinical Study of the Cutaneous Manifestations of Hypothyroidism in Kashmir Valley. Indian J Dermatol. 2013 Jul-Aug;58(4):326.

Safer, J.D. Thyroid hormone action on skin. Dermatoendocrinol. 2011 Jul-Sep;3(3):211-215.

Safer, J.D. Thyroid Hormone and Wound Healing. J Thyroid Res. 2013;2013:1234538.

Selvendran, S.S., et al. Chronic urticaria and thyroid autoimmunity: a perplexing association. Oxf Med Case Reports. 2018 Feb 22;2018(2):omx099.

Stewart, T.J., Bazergy, C. Thyroid autoimmunity in female post-adolescent acne: A case-control study. Dermatoendocrinol. 2017 Dec 12;9(1):e1405198.

Takir, M., et al. Skin findings in autoimmune and non autoimmune thyroid disease with respect to thyroid functional status and healthy controls. Turk J Med Sci. 2017 Jun 12;47(3):764-770.


Akyüz, F., Mutluay Soyer, Ö. Which diseases are risk factors for developing gastroesophageal reflux disease? Turk J Gastroenterol. 2017 Dec;28(Supplement 1):S44-S47.

Carter, D., et al. The Severity of Symptoms Related to Irritable Bowel Syndrome is a Risk Factor for the Misclassification of Significant Organic Disease. J Clin Gastroenterol. 2016 June 24.

Chogle, A., Saps, M. Yield and cost of performing screening tests for constipation in children. Can J Gastroenterol. 2013 Dec;27(12):e35-8.

İlhan, M., et al. Esophagus motility in overt hypothyroidism. J Endocrinol Invest. 2014 Jul;37(7):639-44.

Kopylov, U., et al. Obesity, metabolic syndrome and the risk of development of colonic diverticulosis. Digestion. 2012;86(3):201-5.

Mapel, D.W., et al. The epidemiology and treatment of anal fissures in a population-based cohort. BMC Gastroenterol. 2014 Jul 16;14:129.

Shizuma, T. Concomitant Thyroid Disorders and Inflammatory Bowel Disease: A Literature Review. Biomed Res Int. 2016;2016:5187061.


Brooks, L., et al. Assessing the prevalence of autoimmune, endocrine, gynecologic, and psychiatric comorbidities in an ethnically diverse cohort of female fibromyalgia patients: does the time from hysterectomy provide a clue? J Pain REs. 2015 Aug 20;8:561-9.

Eslamian, F., et al. Electrophysiologic changes in patients with untreated primary hypothyroidism. J Clin Neurophysiol. 2011 Jun;28(3):323-8.

Evans, R.W., Timm, J.S. New Daily Persistent Headache Caused by a Multinodular Goiter and Headaches Associated with Thyroid Disease. Headache. 2017 Feb;57(2):285-289.

Haliloglu, S., et al. Fibromyalgia in patients with thyroid autoimmunity: prevalence and relationship with disease activity. Clin Rheumatol. 2017 Jul;36(7):1617-1621.

Hezarkhani, S., et al. Rheumatologic manifestations in Iranian patients with autoimmune thyroid diseases. J Clin Diagn Res. 2014 Oct;8(10):MC06-8.

Kame, S.S., Bhalerao, N.S. Carpal Tunnel Syndrome in Hypothyroidism. J Clin Diagn Res. 2016 Feb;10(2):OC36-8.

See, L.C., et al. Hyperthyroid and hypothyroid status was strongly associated with gout and weakly associated with hyperuricaemia. PLoS One. 2014 Dec 8;9(12):e114579.

Song, H.S., et al. Association between temporomandibular disorders, chronic diseases, and ophthalmologic and otolaryngology disorders Korean adults: A cross-sectional study. PLoS One. 2018 Jan 31;13(1):e0191336.

Tan, E.K., et al. Restless legs symptoms in thyroid disorders. Parkinsonism Relat Disord. 2004 Mar;10(3):149-51.

Menstrual Disorders

Ajmani, N.S., et al. role of Thyroid Dysfunction in Patients with Menstrual Disorders in Tertiary Care Center of Walled City of Delhi. J Obstet Gynaecol India. 2016 Apr;66(2):115-9.

Digra, M., et al. Thyroid profile in women with menstrual disorders. Int J Reprod Contracept Obstet Gynecol. 2017 Aug;6(8):3300-3305.

Jing, S., et al. Ignored adult primary hypothyroidism presenting chiefly with persistent ovarian cysts: a need for increased awareness. Reprod Biol Endocrinol. 2011;9:119.

Kim, M.H., et al. The relationship between thyroid nodules and uterine fibroids. Endocr J. 2010;57(7):615-21.

Kowalczyk, K., et al. Thyroid disorders in polycystic ovary syndrome. Eur Rev Med Pharmacol Sci. 2017 Jan;21(2):346-360.

Osman, H.A., et al. Precocious puberty: An experience from a major teaching hospital in Central Saudi Arabia. Sudan J Paediatr. 2017;17(1):19-24.

Rajiwade, S.R., et al. Endocrine Abnormalities in Adolescents with Menstrual Disorders. J Obstet Gynaecol India. 2018 Feb;68(1):58-64.

Fertility, Pregnancy & Postpartum

Getahun, D., et al. Association between maternal hypothyroidism and autism spectrum disorders in children. Pediatr Res. 2017 Dec 15.

López-Tinoco, C., et al. Impact of positive thyroid autoimmunity on pregnant women with subclinical hypothyroidism. Endocrinol Diabetes Nutr. 2018 Jan 6.

Martinez, M., et al. Hypothyroidism during pregnancy and its association to perinatal and obstetric morbidity: a review. Endocrinol Diabetes Nutrients. 2018 Feb;65(2):107-113.

Miranda, A., Sousa, N. Maternal hormal milieu influence on fetal brain development. Brain Behav. 2018 Jan 24;8(2):e00920.

Patel, N., Kashanian, J.A. Thyroid Dysfunction and Male Reproductive Physiology. Semin Reprod Med. 2016 Nov;34(6):356-360.

Smith, A., et al. Thyroid disorder in pregnancy and postpartum. Just Prescribed. 2017 Dec;40(6):214-219.

Thompson, W., et al. Maternal thyroid hormone insufficiency during pregnancy and risk of neurodevelopment disorders in offspring. A systematic review and meta-analysis. Clin Endocrinol (Oxf). 2018 Jan 11.


Calzà, L., et al. Thyroid Hormone and the White Matter of the Central Nervous System: From Development to Repair. Vitam Horm. 2018;106:253-281.

Dold, M., et al. Clinical correlates of augmentation/combination treatment strategies in major depressive disorder. Acta Psychiatr Scand. 2018 Feb 28.

Nazou, M., et al. [Psychotic episode due to Hashimoto’s thyroiditis]. Psychiatriki. 2016 Apr-Jun;27(2):144-7.

Pandey, V.P., et al. Verbal Episodic Memory in Young Hypothyroid Patients. Indian J Endocrine Metab. 2017 Nov-Dec;21(6):812-814.

Parikh, N., et al. A case report on myxedema madness: curable psychosis. Indian J Psychol Med. 2014 Jan;36(1):80-1.

Sierra, P., et al. What is the real significance and management of major thyroid disorders in bipolar patients? Rev Psiquiatr Salud Ment. 2014 Apr-Jun;7(2):88-95.

Szlejf, C., et al. Thyrotropin level and cognitive performance: Baseline results from the ELSA-Brasil Study. Psychoneuroendocrinology. 2018 Jan;87:152-158

Tayde, P.S., et al. Hypothyroidism and Depression: Are Cytokines the Link? Indian J Endocrine Metab. 2017 Nov-Dec;21(6):886-892.

Ueno, S., et al. Acute psychosis as an initial manifestation of hypothyroidism: a case report. J Med Case Rep. 2015 Nov 17;9:264.

Kidneys & Bladder

Chang, Y.C., et al. Subclinical and overt hypothyroidism is associated with reduced glomerular filtration rate and proteinuria: a large cross-sectional population study. Sci Rep. 2018 Feb 1;8(1):2031.

Cuna, V., et al. Functional Abnormalities and Thyroid Nodules in Patients with End-stage Renal Disease. In Vivo. 2017 Nov-Dec;31(6):1203-1208.

Da Costa, A.B., et al. High prevalence of subclinical hypothyroidism and nodular thyroid disease in patients on hemodialysis. Hemodial Int. 2016 Jan;20(1):31-7.

Justo, D., et al. Asymptomatic urinary retention in elderly women upon admission to the Internal Medicine department: A prospective study. Neurourol Urodyn. 2017 Mar;36(3):794-797.

Keller, J.J., et al. Comorbidities of bladder pain syndrome/interstitial cystitis: a population-based study. BJU Int. 2012 Dec;110(11 Pt C):E903-9.

Patil, V.P., et al. Evaluation of renal function in subclinical hypothyroidism. J Lab Physicians. 2018 Jan -Mar;10(1):50-55.

Uemura, O., et al. Influence of thyroid function ion glomerular filtration rate and other estimates of kidney function in two pediatric patients. CEN Case Rep. 2018 Feb 28.

Liver & Gallbladder

Duong, N., et al. Case of acute mixed liver injury due to hypothyroidism. BMJ Case Rep. 2018 Jan 23;2018.

He, W., et al. Relationship between Hypothyroidism and Non-Alcoholic Fatty Liver Disease: A Systemic Review and Meta-analysis. Front Endocrine (Lausanne). 2017 Nov 29;8:335.

Laukkharinen, J., et al. The underlying mechanisms: how hypothyroidism affects the formation of common bile duct stones-a review. HPB Surg. 2012;2012:102825.

Oh, R.C., et al. Mildly Elevated Liver Transaminase Levels: Causes and Evaluation. Am Fam Physician. 2017 Dec 1;96(11):709-715.

Rodriguez Lugo, D.A., et al. [Primary biliary cholangitis. Part 1. State of the art, epidemiology, physiopathology and clinical manifestations]. Rev. Gastroenterol Peru. 2017 Oct-Dec;37(4):357-364.

Shabanzadeh, D.M., et al. Screen-detected gallstone disease and autoimmune diseases – A cohort study. Dig Liver Dis. 2018 Jan 31. pii: S1590-8658(18)30141-5.

Sinha, R.A., et al. Direct effects of thyroid hormones on hepatic lipid metabolism. Nat Rev Endocrine. 2018 Feb 23.


Al-Sofiani, M., et al. Hypothyroidism and non-cardiogenic pulmonary edema: are we missing something here? Endocrinol Diabetes Metab Case Rep. 2015;2015:150014.

Condruta, L., et al. Respiratory manifestations in endocrine diseases. Clujul Med. 2016;89(4):459-463.

Fan, Y.M., et al. Prognostic factors for treatment success in patients with multidrug-resistant tuberculosis in China. Int J Tuberc Lung Dis. 2018 Mar 1;22(3):300-305.

Glyn, T., et al. Lessons learnt from a case of missed central hypothyroidism. Endocrinol Diabetes Metab Case Rep. 2017 Dec 2;2017.

Lencu, C., et al. Respiratory manifestations in endocrine diseases. Clujul Med. 2016;89(4):459-463.

Leonardi, A., et al. Pericardial Effusion as a Presenting Symptom of Hashimoto Thyroiditis: A Case Report. Int J Environ Res Public Health. 2017 Dec 14;14(12).pii

Munehisa, F., et al. Respiratory failure associated with hypoventilation in a patient with severe hypothyroidism. Respirol Case Rep. 2014 Jun;2(2):79-80.

Nafae, R.M., et al. Thyroid function in respiratory failure patients. Egyptian Journal of Chest Diseases and Tuberculosis. 2014 Apr;63(2):513-521.

Papaioannou, O., et al. Metabolic Disorders in Chronic Lung Diseases. Front Med (Lausanne). 2018 Jan 18;4:246.

Sadek, S.H. Pulmonary consequences of hypothyroidism. Ann Thorac Med. 2017 Jul-Sep;12(3):204-208.

Sorensen, J.R., et al. Respiratory Manifestations of Hypothyroidism: A Systematic Review. Thyroid. 2016 Nov;26(11):1519-1527.

Ulasli, S.S., et al. Effect of thyroid function on COPD exacerbation frequency: a preliminary study. Multidiscip Respir Med. 2017 Dec 14;14(12). pii: E1576.


Altamirano Ufion, A., et al. Subclinical Hypothyoridism and Its Association with Increased Cardiovascular Mortality. Cardiol Res Pract. 22017;2017:7539735.

Bano, A., et al. Thyroid Function and the Risk of Atherosclerotic Cardiovascular Morbidity and Mortality: The Rotterdam Study. Circ Res. 2017 Dec 8;121(12):1392-1400.

Beukhof, C.M., et al. Effects of Thyrotropin on Peripheral Thyroid Hormone Metabolism and Serum Lipids. Thyroid. 2018 Feb;28(2):168-174.

Binu, A.J., et al. The Heart of the Matter: Cardiac Manifestations of Endocrine Diseases. Indian J Endocrine Metab. 2017 Nov-Dec;21(6):919-925.

Charles, L., et al. Secondary Hypertension: Discovering the Underlying Cause. Am Fam Physician. 2017 Oct 1;96(7):453-461.

Floriani, C., et al. Subclinical thyroid dysfunction and cardiovascular diseases: 2016 update. Our Heart J. 2018 Feb 14;39(7):503-507.

Iaccarino, G., et al. Thyroid function predicts increased cardiovascular risk. Int J Cardiol. 2018 Mar 1;254:338-339.

Iijima, T., et al. Concurrent variant type 3 autoimmune polyglandular syndrome and pulmonary arterial hypertension in a Japanese woman. Endocr J. 2018 Feb 16.

Ionescu, S.D., et al. Massive pericardial effusion associated with hypothyroidism. Rev Med Chir Soc Med Nat Iasi. 2014 Jan-Mar;118(1):87-91.

Lei, L., Mao, Y. Hormone treatments in congestive heart failure. J Int Med Res. 2018 Jan 1:300060518761262.

Lim, H.J., et al. The Relationship between Subclinical Thyroid Disease and Cardiovascular Disease Risk Score in Koreans. J Korean Med Sci. 2017 Oct;32(10):1626-1632

Mourtzinis, G., et al. Primary aldosteronism and thyroid disorders in atrial fibrillation: A Swedish nationwide case-control study. Our J Prev Cardiol. 2018 Jan 1:2047487318759853.

Parent, S., Cujec, B. Subclinical Hypothyroidism and Heart Failure: Chicken or Egg? Can J Cardiol. 2018 Jan;34(1):11-12.

Rizzo, C., et al. Dysthyroidism and Chronic Heart Failure: Pathophysiological Mechanisms and Therapeutic Approaches. Adv Exp Med Biol. 2017 Dec 13.

Sarfo-Kantanka, O., et al. The Effect of Thyroid Dysfunction on the Cardiovascular Risk of Type 2 Diabetes Mellitus Patients in Ghana. J Diabetes Res. 2018 Feb 1;2018:4783093.

Yadav, Y., et al. Cardiovascular Risk Factors in Children and Adolescents with Subclinical Hypothyroidism. Indian J Endocrinol Metab. 2017 Nov-Dec;21(6):823-829.

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About Dana Trentini

I founded Hypothyroid Mom October 2012 in memory of the unborn baby I lost to hypothyroidism. Hypothyroid Mom is for informational purposes only and should not be considered a substitute for consulting your physician regarding medical advice pertaining to your health. Hypothyroid Mom includes affiliate links to favorite resources including the Amazon Services LLC Associates Program. Connect with me on Google+


  1. Very informative. Thank you for putting all this together. You really need to proof read though, there are many spelling errors.

    • Seriously?!! The work this lady has put in and all you comment on spelling errors!

      • Cass Afrass says:

        Spelling is important. If you want a doctor to take this seriously and appreciate all the work that did go into this, then proper spelling is imperative.

        • I completely agree. I just went through the article and made a few changes. Should you find typos or spelling errors that I’ve missed, please let me know. Good to have you at Hypothyroid Mom.

      • My thought exactly!! rude af

      • CELIA MCCOY says:

        Tracy, you took the words out of my mouth. I haven’t even noticed an error because I was too caught up in the wealth of information that she’s shared. It’s because of Dana that I’m more educated on thyroid disorders/disease, this is all new to me and there was so much to learn.
        It’s obvious, the ones that are really concerned with making themselves better and less about correct wording and spelling.
        Keep up the good work Dana!!!

    • I just went through the article again Kim and made changes. Should you find any other typos or errors let me know. This took me over 15 hours to get together. I knew it would take considerable time to create but I really had no idea just how much.

  2. Brigitte says:

    I’m at a total shock of all the symptoms I have. My Dr hasn’t done blood work in over a year. Which last ones t4 was in the 100s. I’m 36 and pretty much have no life. I’m sitting here crying because people including my doctor has accused
    Me of illegal drug use or saying it’s all in my head. The last 2 years. I had went nile, shingles 6 times , flu 4 times can’t count infections immune system disorder yet ONLY medicine I take everyday is for depression and anxiety 1 pill .. thanks to whom ever posted this article.

    • Hi, Brigitte. I’m very sorry you’ve been so sick. Please don’t feel bad about a doctor telling you “it’s all in your head”. Many of us have been told that before. All that means is that they are not the right doctor for you. Ignore that doctor and move on. You need to move on until you find a doctor who can help you. I probably saw almost 15 doctors before I found one who actually helped me. He’s not conveniently located and he doesn’t accept insurance, so I have to deal with the drive to his office and I have to file the claim forms with my insurance company, but when I think about how I used to feel compared to how I feel today, the inconvenience is definitely worth it.

      Here is my advice to you: Read everything you can about thyroid issues. Learn about how the thyroid works, what TSH is, what T3 and T4 are, what the numbers on those tests mean, what the hormones do for your body, etc. There are websites and books where you can find that information. Educate yourself until you can have a thyroid related conversation with your doctor and you can understand everything that’s being said. I have found it very helpful to understand what my own lab reports mean and also to really understand what’s going on when I talk to my doctor. Some people prefer just to take a pill because a doctor says so without really understanding why or what that pill is supposed to do for them. That’s probably ok with some things, but because thyroid issues can be harder to get help with, I think you are better off to be more informed. Some doctors will find an educated patient to be offensive, but if that’s the case, that’s probably just not the right doctor for you. Move on and find a doctor who is not uncomfortable with your knowledge and interest in your own health.

      Look online for good thyroid doctors in your area. People write online reviews about doctors just like they do for other products and services. Read lots of reviews. Call pharmacies in your area and ask if they’ll tell you which doctors are prescribing natural desiccated thyroid medications. In my experience, doctors who are willing to prescribe those types of medicines are usually more informed about thyroid issues in general.

      Once you find a doctor you want to try, print out a list of thyroid symptoms, circle the ones you have and take it with you when you see the doctor. Type up a list of the specific issues you’ve had like shingles and attach that to the list of symptoms. Doing all that ahead of time when you have time to really think about it makes it so that you’re less likely to forget to mention something when you’re at your appointment. When a doctor wants you to have blood tests done, if they only want to do a TSH test, that is a bad sign. A good doctor will also at least look at Free T3 and Free T4. There are other thyroid related blood tests they can also do, but if they won’t at least do those two in addition to the TSH test, don’t even bother to go to the lab and get blood drawn. Just move on to the next doctor. When you call to schedule an appointment, feel free to ask what labs they run for a thyroid appointment. You may be able to eliminate a doctor that way before you even see them. Once a doctor runs blood tests, ask for a copy of the lab report. If you have to move on again and see another doctor, take that lab report with you to your next appointment in addition to the list of symptoms. If it’s recent enough, the new doctor might not make you redo the lab work.

      If you have a bad feeling about a doctor from the beginning or realize they’re not helping you after a couple of appointments, move on. If you’re still feeling badly but the doctor tell you that your lab report says you’re fine and that’s the end of the conversation, you need to move on. You need to find a doctor who doesn’t just look at the lab report, but also cares about how you’re feeling. Keep moving on until you find the right fit. When you try on shoes, you keep trying them on until you find the right fit. Do the same with your doctor. Never go back to a doctor who isn’t helping you. That’s just a waste of your time and money. You are the customer in the doctor-patient relationship. If a doctor is not providing good service, don’t keep going there and don’t feel bad about not going back. Out of all the doctors I tried, not one ever called me up to ask why I didn’t go back. You will not be hurting their feelings. Don’t look at moving on from a doctor as a bad thing. Look at it as you’re one step closer to finding the right doctor. Once you find a doctor who does actually help you to feel better, you will be very glad you put in the effort to find them, and hopefully, you will end up feeling much better.

      Keep in mind, this can be a long process. There is often a long waiting period to get an appointment with a good doctor. Don’t be afraid to make appointments at multiple places, especially if one has a three month wait and one has a six month wait. If you don’t like the doctor with the three month wait, you’ll already be half way through the six month wait when you figure that out. You can always cancel any appointments you don’t need. Just make sure to keep track of each office’s cancellation policy so you don’t end up paying a fee for canceling. Good luck to you!

      • Very good advice. Most Drs. treat this as an emotional problem instead of a disease. One Dr. ask me if I felt suicidal. Well of course I am not the happiest camper around because I had an accident that broke my arm and back. So therefore I had to retire before I was ready and always have been active. But this is not why I feel bad all the time. I do have a goiter, and nodules on my thyroid, kidney and one lung. This all came up after my fall. I have gained over 60 lbs. and normally for my whole life I was thin. I test out 106/310 on that test. But I could not answer several ones because I am past child bearing years so them were a 0. Plus some I could not answer because I do not know if I have some of the conditions they ask. When I take the test they are within a normal range and the Drs. go by this more than your symptoms, such as joint pains, severe fatigue, dry skin, hair loss, skin breakouts, never feeling refreshed on waking up, insomnia, constipation etc. etc. etc. All I ever have gotten from a visit to the Drs. is, “Call me if you want to talk”. I didn’t go in there to talk I wanted some results, I have been put on any kinds of meds for this or even given a diet to follow. I heard of a Dr. Herr in Chester, PA who will give you a complete work up and then prescribe what the best way to approach your problems with this, but they do not except Health Ins. so this leave me leery that they may not be legitimate Drs. I would go to them in a minute if they excepted my Ins. Have you heard of them?

    • Brigitte, This article was on my mind for many months. I knew it was necessary but I also knew it would take me so many hours to sift through the scientific literature. I’m happy that I got it together here because I hoped that it would show my Hypothyroid Mom readers that their symptoms are not all in their head. Of course not everything will be thyroid related but this article shows without a shadow of a doubt that hypothyroidism can affect every part of the body. This is your red flag to find a new thyroid doctor. Here are resources that I hope will be helpful in your search. Don’t restrict your search to doctors only in your city because it is well worth a long distance drive to a great doctor.


  3. I’m really glad to have found your page and this article. Thank you for the hard work you’ve put in to this article. Two things: first, I am swinging between Grave’s and Hashimoto’s. Hyperthyroid has been mostly what I have dealt with, though I am currently hypo. Is there a list anywhere like this for Grave’s? Second, it is very difficult to read many of the lists with the color of font over a busy background picture. Is there a way to make this more readable? Especially in a mobile device, there were a few lists I had to skip because I just couldn’t see them. For doctored to take this more seriously, they need to see it easily as well. Thanks again for what you have done here.

    • Cindy P says:

      Well said. I thought the exact same thing about the font colors over the pictures… hard to read and not professional enough for such a serious medical condition !
      Very good information!

      • I hear you Cindy. I’ve had several people mention that they would prefer the lists of symptoms without the background images. When I have a few hours to spare I’ll be sure to update this article with plain white background.

    • Hi Kara, I plan to modify this article in the near future to plain white background so that the words are easier to read. As for information about Graves’ disease, Elaine Moore has a good website: http://elaine-moore.com

  4. Hi Dana, appreciate all the hard work. I have 120 of the symptoms on this list, I am on thyroid meds but I believe I need a higher dose, I think I will change doctors. Thanks again!

  5. barbara says:

    your work is much appreciated. I have 14 of the Symptoms on the list and Doctors are not very help full Just put you on the regualr Meds and thinking thats all, but it is not. I had a chat with my Doctor in Germany and she was very concerned about that , on Top of my Thyroid problems I was bitten by a Tick last Summer and I was given a round of Antibiotics. My Doctor in Germany mention ,it could be very well that I have some form of Tick born Disease , which can mimic also up to 300 differnt symptoms of diseases . But I will return in a couple weeks back to my Home Country and will get the Help I need

  6. Doreen Hrycun says:

    Thanks for all this great information!
    One of my major concerns is my head sweats most of the time. I’m always so conscience and embarrased by my dripping wet hair. What causes this? The rest of my body is fine, it’s just my hair root to tip. Help!

    • Kristina says:

      OMG this happens to me as well! Specially in line at the store when checking out then I get anxious and embarrassed people probably think I’m sick or something because it’s definitely noticable

  7. Kristina says:

    Thank you so much for sharing all your hard work And dedication with others.
    I am 32 and have struggled with hypothyroidism since 20 I have tried so hard to get help from many different doctors and just barely getting by day to day through the years i hate it. I scored 157 out of the 310. I am currently on 275mcg of levrothyroxine I’ve lost more than 1/2 of my hair feel tired run down sluggish daily pale dark circles Achey soar swelling I mean I am a mess and doctors don’t help thank you for all your help I’m going to push even harder now with doctors now that I have all this wonderful info!

  8. Just had thyroid retested today, last time the doctor told me I was both hypo and hypothyroid! What the heck does that mean?. I have 101 of the 310 symptoms. May I ask what Graves and Hiroshimito is and what is the difference? I have gained over 35 pounds in the last 5 yrs, I am really getting scared. Thanks so much for all your info and the list is way more important than the spelling or font! Thank you.

    • Meant to say hyper a d hypothyroid! Tests came back ok, so keep up with synthroid! Still confused, why do tired and gaining weight?

  9. Rochelle says:

    Very impressed with all the recent research papers that you have provided! My profs of yesteryear would applaud you!
    Thanks for all you share with us.

  10. Many thanks for this Dana i was amazed to find i scored 92 and I am one of those people who have been told for years there was nothing wrong with my thyroid..its a shame that few doctors actually look at the patient in front of them any more!. You asked about spelling mistakes, under Energy & lack of sleep: “Lack of concentratioM”
    and under Heart: “HighT or low blood pressure”. Hope thats of help. Thanks again.

  11. Kathleen says:

    I have over 100 symptoms. Yet, my thyroid is fine! I have several nodules, which have been biopsied at scar tissue. I am on two different thyroid meds, yet I continue to suffer. They say I have Hashimoto’s but don’t know why…. I have a PCP Internist, Rheumy, Endo, Pulmonologist, and none of them are working with each other. Take this pill and see you in six months….

  12. Are there any outstanding thyroid doctors on-line for a face-to-face appointment?

  13. Dana, let me tell you how much I appreciate all of your articles and the hard research you’ve done to inform us about these diseases. I only have 76 of these symptoms and most of them were the brain issues. I recently retired, and had planned on finding a part time job, but I can’t remember anything, I’m unteachable, I can’t retain anything, I’m tired all the time, so why look for work??
    I just read an article for The spouse. Great article, I had my husband read it. His first comment was “I had no idea!” He had gotten on me one day cuz the floor needed sweeping, things around the house weren’t done. I’ve been telling him I’m tired all the time and I do what I can. Well, that article made all the difference, and he apologized to me! I’m pretty sure it was on your page. I’m just now seeing a endo, I was just going to my pcp. The first thing the Endo told me was “You’re dose is way too high!” (Armour Thyroid 120mg). So I’m hoping this Dr will help me get better. Now that I’ve written a novel, I just want to thank you for all the information you post, and I don’t care about what font or spelling, keep it up!!

  14. Brigette says:

    Dear Dana
    I have a relitive that has been told by he GP here in the U.K. that she has to wait for her thyroid to burn out before they will do anything for her. She like me has Hashimoto’s Hypothyroidism and is increasingly getting worse. I am very concerned for her. Could you please list for me why it would be better for her not to wait for her thyroid to burn out? I have googled the question, but not had much luck. I am thinking of going with her if I can get her to her GP, or do you think we should see another GP in her practise. She is not on any medication for Hashimoto’s and I think she should be and should be referred to an endocrinologist, but I think this is going to incredibly difficult to get done!
    Kind regards Brigette

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