The Truth About Hypothyroidism And Depression

The Truth About Hypothyroidism and Depression

I was contacted by a reader with a story that drove straight to my soul. Her story hit me so hard that I sat motionless with my head down on my desk. If you’ve ever questioned the seriousness of hypothyroidism, that ends today right now with this post.

I had my first child at 27 and all was well. Within 3 months I was back to my normal size. Life was wonderful and I was a wonderful mother.

I have always been a fun loving person who loved to laugh. Having such a great child, I wanted another one. It took me 9 months before I became pregnant with my 2nd child. Immediately I started getting sick. Sick as in I was always hungry. If I didn’t eat immediately upon waking I would get sick. I rapidly began packing on pounds and was extremely tired and moody. I had a short fuse at all times. At 8 weeks I started bleeding and had a miscarriage. After losing the baby I could not lose the weight I had gained. I was 29 and the doc said that our metabolism slows down as we get older. Diets didn’t help.

I became pregnant with my son within 3 months of miscarrying. Started off the same. I was sick if I didn’t eat. I slept all day and was extremely tired. My 3-yr old daughter who I couldn’t get enough of spent my whole pregnancy watching TV while mommy slept. Again I was extremely cranky. My hair began falling out and I was extremely hot and would often wake up covered in sweat. I was out of breath all the time. I gained over 75lbs. By the end I couldn’t walk. Just lifting my leg caused pain. I asked the doc to check my thyroid and he said it was a normal pregnancy issue.

After he was born I had extreme postpartum depression. To the point that less than 1 hour after my son’s birth I kept envisioning myself picking him up and throwing him up against the wall. My son had colic and cried all the time. I suffered from extreme exhaustion and lack of sleep. My only way of dealing with it was to cuss him out. I wanted to hurt him but would never let myself.

After my 6 week check up I found another doc. I begged her to check my thyroid. She did and my TSH came back at 100.

The Truth About Antidepressants

The Dr. Oz Show aired a show called The Truth About Antidepressants.

The Dr. Oz Show conducted their own survey online and found that “72% of women who were prescribed an antidepressant did NOT receive ANY other medical workup by the doctor first. This is critical because often times medical conditions will mimic depression and we know that when you properly diagnose and treat that underlying medical problem the depression will go away. Doctors may sometimes misdiagnose women with depression if you really have”:






Before anyone starts taking an antidepressant, they should have complete medical workup done to determine if underlying medical issues including low thyroid are the cause of the depression. The problem is that there is so little awareness about thyroid conditions. There are millions of undiagnosed thyroid sufferers worldwide. How many of them have been misdiagnosed with depression? I hope this article reaches them.

Hypothyroidism & Depression

I have received countless messages from hypothyroid women on antidepressants. You only need one look at my posts When Thyroid Disease Masquerades As Psychiatric Disorder and Mental Disorder or Undiagnosed Hypothyroidism to know there is compelling research linking hypothyroidism to mental health symptoms.

If you are hypothyroid and on antidepressants, what should you do?

Please speak with your doctor about taking a closer look at your thyroid condition. Be sure that thyroid testing includes at a minimum TSH, Free T4, Free T3, Reverse T3 and thyroid antibodies. Do you suffer from other hypothyroidism symptoms? Are you certain you are being optimally treated for your thyroid condition?

It is particularly interesting to me that in addition to low thyroid function, Dr. Oz listed anemia, PCOS, Celiac Disease and PMS as potential underlying medical conditions for depression.

  • Anemia – Abnormal iron levels are a common problem for hypothyroidism sufferers so be sure to have a full iron panel including ferritin included in testing for anemia.
  • PCOS – I wonder how many PCOS sufferers are aware of the thyroid connection especially the link to the thyroid autoimmune condition Hashimoto’s Thyroiditis.
  • Celiac Disease – As with PCOS, Celiac Disease has been linked to Hashimoto’s so be sure to have your thyroid antibodies (both Thyroid Peroxidase Antibodies & Thyroglobulin Antibodies) tested.
  • PMS – PMS is a real issue for hypothyroid women. This is not a surprise really given the intricate connection between sex hormone levels and the thyroid. Be sure to have your sex hormones including testosterone tested.

Do not just stop taking your antidepressants. Please speak with your doctor and if you decide to stop the antidepressants be sure to have close medical supervision during that weaning off phase.

This is not to suggest that antidepressants are not necessary and helpful for many people. There is no shame in taking antidepressants. That’s not what this article is about. The issue is that every person suffering from depression should have complete medical workup including thyroid testing to ensure all potential medical conditions that mimic depression have been fully investigated.

My fear is that there are many more hypothyroidism sufferers misdiagnosed with depression than anyone realizes.


  1. Kantor, E. D., Rehm, C. D., Haas, J. S., Chan, A. T., & Giovannucci, E. L. Trends in Prescription Drug Use Among Adults in the United States From 1999-2012. JAMA 2015, 314(17), 1818-1831.\

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About Dana Trentini

Dana Trentini M.A., Ed.M., founded Hypothyroid Mom October 2012 in memory of the unborn baby she lost to hypothyroidism. This is for informational purposes only and should not be considered a substitute for consulting your physician regarding medical advice pertaining to your health. Hypothyroid Mom includes affiliate links including the Amazon Services LLC Associates Program.


  1. Dear Mrs. Trentini, Thank you for your website.

    I have osteoporosis and hashimotos thyroid as well as another immune disorder.

    I was born with osteopinia because my mother didn’t have any prenatal care. I was born with weak bones before being diagnosed with hashimotos thyroid.

    I am worried about not being giving the optimal dosage of thyroid medication or at at least the minimum dose to avoid psychiatric symptoms because the doctors always worry about the condition of my bones. I repeatedly have to “remind” the doctors that My brain is more important to me than my bones. I am on thyroid medication but I feel horrible. I have never felt depression, hopelessness, despair, and disappointment in the medical system like I have now. Any advice you could give I would appreciate.

  2. Recently got diagnosed with hypothyroidism, also I have been taking 2 antidepressants for major depression for a year now.
    I asked my doctor to test for my thyroid levels after a friend told me to get it checked out after talking to her what I have been dealing with, weight gain ,muscle aches, tiered all the time, no focus etc etc..
    My doctor doesn’t want to take me off the antidepressants because he says that my thyroid doesn’t cause my depression and it works well, he even wanted to put me on another antidepressants because of insomnia..

    • I’m 73 and suffered from depression most of my life, and finally got treatment after my Ex husband wanted a divorce. Was on and off antidepressants for years and didn’t have insurance so went without medical care for awhile. Menopause was not fun but things improved a little after I moved away from a stressful area and then I started having new weird symptoms. Finally got on Medicare and didn’t get much help when I told Drs. I had most of the Hypothyroid symptoms. My tests showed everything was within normal range. I did did an at home blood test that showed my TSH level was abnormal (high) but Dr. said they weren’t reliable, and my lab work at that clinic came back normal. I’m trying to manage my health issues on my own and take various supplements and will find another Dr. if my symptoms don’t improve.

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